MME9107: Biomaterials and Tissue Engineering

This course is designed to impart an understanding of how materials should be designed for optimal results in tissue engineering. An additional aim is to understand how cells and proteins interact with materials. 
 
Course objectives 

• To understand the biological requirement for designed tissue engineering systems 
• To design scaffolds for growing biological materials 
• To fabricate multicomponent biomaterials using advanced manufacturing technologies including 3D printing. 
• To design diagnostic and drug materials systems. 
• To design a biomaterial system considering the main issues of biocompatibility including toxicity. 

 
Learning Outcomes

Knowledge and understanding  

• Analyze advantages and disadvantages of methods for scaffold fabrication 
• Discuss advantages and disadvantages of commercial materials that are used in tissue engineering today 
• Explain how material properties influence the cell response. 
• Explain different techniques for cell identification and quantification of cell properties  
• Describe the regulations and ethics in tissue engineering  
• Understand the fundamental principals in biomedical engineering, material science and chemistry, and how they contribute to biomaterial development and performance. 
• Apply the math, science, and engineering knowledge gained in the course to biomaterial selection and design. 
• Critically review papers from the scientific literature and identify areas of research opportunities  
• Understanding the Fundamentals in design, fabrication and selection of biomaterials for medical applications. 
• Familiarizing with the physical, chemical and mechanical properties and bio-compatibility of different types of biomaterials, e.g. natural, synthetic, inorganic and composite, etc. for the basis of tissue engineering. 
• Applying the principles of tissue engineering for medical application. 
• Considering the physical and biological concerns of biomaterials applications in clinical indications 
• Skills and abilities  
• Experience in engineering scripting languages 
• Complex geometric modeling 
• Running flow solver routines 

 
Ability of assessment and attitude  

• Apply CFD methods in modeling of engineering processes in environment, construction and health 
• Ability to model products obtained from CAD and apply CFD  
• Apply the finite volume models and their challenges in everyday life.